![]() The Epson Duet Ultra Portable is a true multipurpose projector screen, with the ability to serve as a business presentation tool or as an affordable entertainment screen. Most have different power settings, which gives you some control over how long they’ll last, but in general you should expect to get through one or two movies without much trouble. Battery life: Portable projectors are a battery power balancing act: brightness, speaker size, weight, and resolution all play a part in how much time you’ll get to use them per charge.That said, the speakers are generally smaller, and less powerful because of space restraints, and can add to power consumption. Speakers: All of the portable projectors on this list have built-in speakers, so you don’t have to carry a pair around with you to watch a movie.All of the projectors on our list weigh less than five pounds, and will fit in a backpack, but this is definitely a factor to consider if you’re planning on carrying your projector around a lot. ![]()
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Process individual Polylines or groups of 2D or 3D Polylines.Most edits require less than three picks.Works with 3D Polylines, Regular 2D and LW Polylines.Draw legal description faster and more accurately Even though I know it's the iconic Warlock to a lot of people. I'm not familiar with the older 3.x Warlock, but I hear it was a blaster and that doesn't scream "Warlock" to me. I definitely don't think we need to worry that PF2's just going to port over the 5e Warlock or anything I think the Witch is as close as we're likely to get, and those two are really nothing alike besides "Patron" and "Familiar" and "I'll use my leftover action to Hex". What do you envision such a class being like? I'd love a bit of a darker, fairy-tale inspired casting class, if that's what you mean. I just want to play a warlock in Pathfinder. I really don't want the D&D Warlock and the Pathfinder Warlock to be similar in any way. Not a copy of the D&D Warlock I want Pathfinder to have a new class name Warlock. I haven't thought it through or anything, so this all might be very silly. Or Improvised proficiency, which I think they should maybe get as a 1st-level Class Feat.īasically, I want the Polytool as a class. What else could you possibly need? Melee d12s are for people who don't have environmental trickery and a grappling hook. Proficiency in Unarmed, Simple, some tool-adjacent Martials and the Polytool. Every tool should have at least three functions, and at least one of those functions should be "ow". Grappling hooks used to grapple, kickin' folks with leaper-boots, thieves' tools for combat tricks and stuff like that. In combat, I'm thinking that a cool niche would be using explicitly utility-based abilities to lay down effects and deal damage. A sort of Wizard-Rogue to the Occultist's Bard, perhaps, though with magic as one tool of many rather than The Point. Or more like the Technician, for those familiar with Spheres, with a touch more magic, like the Scroll Trickster. What the Psychometrist Vigilante was sort of trying to be, but really honed as its own concept. I'd love an item-focused class not necessarily The Crafter but more like a true utility-to-combat gadgeteer with a very Pathfinder twist. Guns shouldn't be restricted to a single class, and it was so problematic in PF1 as a result that almost every class got a Gun archetype to resolve the issue.īut the guns are soo cool maybe instead of beating AC you attack vs Reflex save The most suggested propositions are to include the Ronin/Samurai as well as the Cutthroat with thrown knives and various other "cool hand split second decision" fighters. When they say additional styles of weapons, they don't mean additional guns. Spell-slinger - magic bullets/casting through the gun. ![]() Rifleman/sniper - sneak attack with rifle of course they where also able to be used on horseback during the 100 years war unlike the PHB ![]() Of course the is a longbow was also around 900 ft. Where as a rifled one around the same time period had an effective range of 1500 ft 5918 The traditional smooth bore musket had an effective range of 900 ft (human sized target) because PF2 is in the future of PF1 rifling might be developed Like, say, a class built around Fortune effects.įor the gunslinger there are a few great possibilities: They did a lot of new things with the magic system in PF2 I would have liked to have seen a class inspired directly by those changes, instead of working with the changes to evoke a PF1 class. ![]() I'm a little disappointed SoM didn't try to squeeze one in. The only outstanding "needs to be done" class is the Gunslinger, and I know many of us hope that the Gunslinger grit mechanics will be attached to more general "Man without name" class concept. I think we'll start seeing original classes after this round of books. ![]() ![]() The prices are subject to change, but Bitdefender will send a prior notification by email, before the automatic renewal takes place. You will receive an email notification before you will be billed, along with information regarding pricing and the extension of your subscription duration. Removes adware and unwanted programs Aggressively targets adware, spyware, potentially unwanted programs (PUPs), and browser hijackers with technology specially engineered to remove these threats. If a discount is presented, it describes the difference between the first term and renewal term subscription prices (e.g., first year price vs. It’s the cleaner of choice for home users and technicians.After that, your subscription will be billed at the applicable renewal price which may be higher than the initial purchase price The price offered is valid for the first year of subscription.Check our guide on how to remove malware from Mac. And there is even more distressing statistics we found: on average, there are three adware infections per user hiding on a typical Mac. 24/7 security all-subscription long without interruption MacKeepers adware removal tool detects adware on as many as 66 of all computers.Opt out at any time so that you are always in control of your renewal options.Save time while we are taking care of the automatic renewal process.and then just use basic av/anti-malware tools, have a home router, keep your firewall on, use ad and script blockers in your browser. Peace of mind that your devices are always protected if you have a cheap/slow pc/laptop with no hardware problems, the best thing you can do is reinstall the os minus all the crapware your manufacturer put on.Free upgrades whenever a new version of Bitdefender comes out.Continuous protection so that you never have to worry about your subscription running out before you renew manually. Catalana Shares His Favorite Onsite Pediatric Board Review Course Memoryĭr. You can read more about this in the StudyWise guide.ĭr. People study in different ways, and I really think it will behoove you as you prepare for your boards to just briefly read some of the literature about how we learn as adults. Take a little while to remind yourself how you best study. But, I think making a plan, sticking to that plan, and finding a few proven resources will help. So, accept the fact that it is important, but do your best to not let its importance overcome you to the point where you let stress and anxiety interfere with your ability to study. In the past, not all that long ago, it was nice to be certified, but it was not a requirement for medical staff privileges and the like. I don’t think that we can ignore the fact that the importance of the exams and of certification is paramount. What advice do you have for those preparing for exams? That is when we potentially put patients at risk, and none of us wants to do that. Realize that it is far better to ask a question and to say “I don’t know” than it is to assume you know or have too much pride to admit that you don’t know. ![]() I think that we all need to encourage one another to work as a team and to bring out the best in each other. I think that during your residency you think that you have to know it all, and I have certainly come to realize that you will never know it all. What is something you wish you had known during your residency? I think that, for a variety of reasons, that helps you to clear your mind and gets you ready for the next day. What is one of your self-care tips?ĭon’t take yourself too seriously and exercise. Catalana gave us some inside info on his self-care and exam tips. Catalana’s Guidance on Studying and Exam Prepĭr. So, I enjoy mentoring and counseling, and there is no better reward than to run into an old student or resident, sometimes even years down the road, and see them succeeding.ĭr. This profession is tough, and sometimes we don’t do as well as we ought to at following our own advice about taking care of ourselves. A lot of that involves encouraging people to take care of themselves. Most of what I do now, besides teach, is advise on how to get into medical school and how to perform well in medical school. What is the most rewarding part of your current position? Most of it is happy, and even when children are sick, their spirit and incredible resilience is a blessing. ![]() They make me not take myself too seriously. I think more importantly, their energy, their resilience, the fact that they don’t take themselves too seriously. I don’t think I ever had any doubts that pediatrics was what I wanted to do. How did you know Pediatrics was right for you? Originally, I was going to be a teacher, but, following a serious automobile accident that put my mom in the hospital for six weeks, with me in the car as well, I was exposed to a lot of things, and it really generated my interest in going to medical school. When did you know you wanted to be a doctor? ![]() We wanted to get some background on what lead him to his current role. Catalana is the Pediatric Board Review Course Co-Director and a student mentor, he knows a thing or two about teaching. Catalana working on the most recent edition of the Pediatrics Core Audio Pearls We're honestly not sure what we'd do without him!ĭr. He has also been a go-to for countless other study solutions for Pediatricians including the Audio Pearls, MOCA-Peds QuickRef, Pediatrics Core, Peds Q&As, and our most recent Medical Student Study Strong System. Catalana's Growth & Development lecture from a Pediatric Board Review Course Catalana serves as the Course Co-Director, which means he is onsite with us in the office (and was onsite at course locations with us pre-COVID) answering questions from attendees, delivering lectures he is highly specialized in, and helps manage the day-to-day course happenings!ĭr. He is currently Senior Associate Dean for Student Affairs and Admissions at the University of South Carolina School of Medicine-Greenville in Greenville, SC.ĭuring our Pediatrics Board Review Courses, Dr. He went to school at the State University of New York at Stony Brook and did his Pediatric Residency at Prisma Health–Upstate, formerly Greenville Health System. Catalana has been working with MedStudy since 2012 to bring Pediatricians the best in high-yield Pediatrics review materials. Catalana’s Background and Passion for Teachingĭr. Here's an inside look at what he had to say about the Pediatric Board Review Course and advice for those preparing for upcoming exams. During our last Pediatric Board Review Course, we were able to pull Paul Catalana, MD, MPH, FAAP aside from his course duties and talk with him about his background, passion for teaching, and medical education. ![]() Additionally, the concept of "dark matter" appears as the medium of which Cosmic Clones are composed, and as a portal through which Airships emerge. Launch Stars reappear for interplanetary navigation, along with a Luma and Mario's spin action. Power-ups, such as the Bee Mushroom, Boo Mushroom, Spring Mushroom, and Fire Flower make a return, along with new ones such as the Rock Mushroom and the Cloud Flower, as well as various enemies and Airships. The gameplay is similar to Super Mario Galaxy, with a focus on platforming based on and around 3D planets of varying sizes and with many different types of surfaces. During his travels, Mario has to deal with Bowser's forces, including Bowser Jr. Realizing both him and Mario need each others' help to collect the stolen Power Stars and rescue Peach, he uses the Power Star to fix his ship and transform it into Starship Mario, which is used to travel through space and find more Power Stars. In response, Lumas who crashed near the castle offer to aid Mario to chase Bowser by transforming into a Launch Star and launching Mario to space.Īfter collecting a Power Star, Mario arrives on a planet-like object, where he meets Lubba, who tells him that his crew and their spaceship were attacked by Bowser. ![]() Near the castle, Mario discovers it under attack by Bowser, now gigantic thanks to the Power Stars, who kidnaps Peach and takes her away to the center of the universe. On his way to Peach's Castle, Mario finds a lost Baby Luma, who seems to like Mario and jumps into his hat, granting him spin power. Princess Peach invites Mario to share some cake while watching the shooting stars. ![]() The game begins at the time of the Star Festival, which only happens every 100 years. ![]() Super Mario Galaxy 2 is "another story of stardust". But when he got there, something unexpected was waiting for him… With the baby Luma tucked safely under his cap, Mario rushed on to the castle. As he peered cautiously through the reeds, he saw a small, lost Luma. Suddenly, he noticed a strange light in the grass. Mario ran through the field with stars falling around him. That time had come again.ĭear Mario, Would you like to share some cake while we watch the shooting stars? Meet me at the castle! Peach Shining stardust falls on the Mushroom Kingdom once every hundred years.
![]() John H, owner of a 2017 Toyota Tacoma from Fayetteville, NC Since I was only painting interior pieces it was not a problem but if I would have tried to paint exterior prices and color match the paint it would have not worked very well. My only complaint is that the paint was a few shades darker than the paint on the truck. The products were very easy to use and had a great look and finish to them. I purchased some spray cans of paint, adhesion promoter and clear coat for some trim pieces on the inside of my truck. Ken, owner of a 2017 Toyota Tacoma from Azusa, CA Thank you!ĭoylestown PA Steven G, owner of a 2017 Toyota Tacoma from Staten Island, NY Applied the paint to the chip and the results were great. The color was a perfect match for my white 2017 Toyota Tacoma. ![]() Saved me some $$$ Jim S, owner of a 2017 Toyota Tacoma from Doylestown, PA Gordon G, owner of a 2017 Toyota Tacoma from Mechanicville, NY Good product, great price but the color was a little bit off. John F Delvalle, owner of a 2017 Toyota Tacoma from Lake Worth, FL Over the years I’ve used Automotive Touch up on all my vehicles with excellent success (spray can) but this last experience was disappointing (Toyota Tacoma White touch up paint) The paint color was considerably darker then the stock Toyota White and it was hard to get a smooth application and required sanding. ![]() Here's what our customers are saying about our Touch Up Paint: Roland T, owner of a 2017 Toyota Tacoma from Arlington, VA See the cabinet art and move-list here (note: external links might be shut down and there’s nothing we could possibly do about it, sorry for the inconvenience if this is the case). Download - Easy Setup (699 MB) Cadillacs and Dinosaurs: The Second Cataclysm screenshots: A third-person driving and shooting game, based on the comic series Xenozoic Tales by Mark Shultz. What do you guess? Now, yes! An eight-way joystick and two buttons (though for some strange reason, MAME lists three buttons in the settings tab), button one for attack and pick-up and button two for jump. Sounds and visuals are pretty ok for a 1993 game, though it wouldn’t hurt if the sprites were a bit sharper, I guess, but hey-if the scenes look real enough and do not make you want to puke and scratch your eyes out of your head, what’s there more to ask for?Ĭontrols? Well. ![]() And anything not featuring enough dinosaurs was inevitably out. And after the first Spielberg’s take on Jurassic Park appeared on the silver screen, they were a thing even more. And being a millennial kid, I can tell you that dinosaurs were a thing back then. But the unique combination of Fallout Style retro-future apocalypse combined with the Arthur Conan Doyle’s Lost World elements were definitely something new. Like, we’ve seen games based on a comic book a million times before. And since I’ve got to read some of the comic stories only after I’ve first played the game itself, I can only imagine what it must have been like for the comic fans when they first popped that coin into the cabinet. But what makes Cadillacs and Dinosaur so fun is its settings and atmosphere. I mean, it’s a perfectly good and fun brawler on its own. And, well, that’s not where it exactly excels. Now, gameplay-wise, Cadillacs and Dinosaurs are pretty much your average Capcom-style brawler: isometric view and movement, four characters to choose from (up to three players can play simultaneously), destructible surroundings (which usually yields you some kind of reward like bonus score points or HPs), weapon pick-ups-you get the idea. ![]() There the protagonists, the eponymous Cadillacs, named after their ‘sort of leader’ Jack “Cadillac” Tenrec, find themselves fighting a group of poachers called Black Marketeers, who (for unknown reasons) hunt and capture wild dinosaurs, which makes the animals afraid of-and thus hostile towards-humans, breaking the fragile equilibrum between the surviving humanity and the new thriving ecosystem. Half naked chicks, dinosaurs, vintage rides and guns in a single package, you say? Well, count me in!īased on the popular 1990’s comic book series titled Xenozoic Tales (or C&D), Cadillacs and Dinosaurs follow the same group of characters (from the comic) living in a post-apocalyptic 26th century, in which the Earth (after the humanity took refuge in underground shelters for circa six hundred years) has been repopulated by previously extinct species, namely dinosaurs and prehistoric creatures. ![]() Description of Cadillacs and Dinosaurs ROM - MAME Su patogénesis se caracteriza principalmente por la muerte selectiva de las motoneuronas (MN) en corteza, tronco del encéfalo y médula espinal. La esclerosis lateral amiotrófica (ELA) es una enfermedad de la edad adulta. As disease pathogenesis remains obscure, the search of therapeutic targets to slow disease progression in ALS, remains puzzling. In conclusion, why MN selectively die in ALS disease, remains a mystery On the other hand, it seems that other cell types are also affected, particularly at the sympathoadrenal axis. Upon its chronic administration to SOD1 G93A, we found that the compound delayed disease onset but only in females mice. Furthermore, we found that these alterations could be related to the accumulation of mutated SOD1 into mitochondria this resulted in mitochondrial depolarization, excess production of reactive oxygen species and deficiency in oxidative phosphorylation.įinally, we discuss recent data on the potential therapeutic effect of compound JNJ-47965567, a blocker of P2X7Rs known to be central-stage in neuroinflammation. In CCs, we found deep distortions of the exocytotic kinetics and the exocytotic fusion pore in the process of catecholamine release, in the SOD1 G93A mouse model of ALS. ![]() In our laboratory we found that CSF from ALS patients exerted toxic effects on cultured cortical MNs. This indicates that a kind of toxin agent may be released and propagated through the CSF. ![]() In this review we focus on four aspects: (i) the hypothesis of disease propagation through the cerebrospinal fluid (CSF) (ii) the distortion of the exocytotic release of neurotransmitters at the sympathoadrenal axis (iii) the ultrastructural and functional alterations of mitochondria from adrenal medullary chromaffin cells (CCs) and (iv) the purinergic P2X7 receptor (P2X7R) as a potential target for neuroprotection.Ĭoncerning disease propagation from one to another area of the central nervous system (CNS), the pattern of clinical progression suggests that the disease spreads centrifugally. Amyotrophic lateral sclerosis (ALS), an adult onset, fatal neurodegenerative disease, has as a cardinal pathogenic feature the selective death of motor neurons (MNs) at the cortex, brainstem, and spinal cord. ![]() The voltage can be set between 5 and 12 volts in 0,5 V increments using the two arrow keys. In addition to the capacity and voltage LED display, the PowerBolt battery has three buttons: two buttons for setting the voltage and one button for switching on and off. You can also connect to an Apple or Android application via Bluetooth and update Spektra Flux at any time using the latest firmware. Spektra Flux also has a Bluetooth interface, through which the FK Irons hover power supply can be connected. The PowerBolt battery is easily connected to a power source using a USB-C cable. This means that even if the battery and, if necessary, the replacement battery are empty, you can continue to work with the USB-C cable. Thanks to the dynamic control of the power path, the battery can be powered and charged simultaneously. The PowerBolt battery lasts up to 10 hours and can be fully charged up to 1.5 A in a very short time via a USB-C connection. We have created a wireless device with up to 10 hours of battery life with a fast charging speed. Just a pen-style device with all the features you need. More power without any of the complicated stuff. The PowerBolt lithium-ion battery allows comfortable work without a power supply and cables. The first truly wireless tattoo machine is here the Spektra Flux. It is therefore suitable as a universal accessory for all tattoo styles. It is driven directly, ie without suspension, and has a stroke of 4 mm. The PowerBolt Spektra Flux is the successor to the internationally popular Spektra Xion tattoo machine and the first wireless tattoo pen from FK Irons. FK Irons – wireless tattoo machine Spektra Flux including 1x battery. Risk factors for prediabetes and Type 2 diabetes include: Exposure to illnesses caused by viruses.Physical stress (such as surgery or illness).Presence of autoantibodies (antibodies that mistakenly attack your own body’s tissues or organs).Injury to the pancreas (such as by infection, tumor, surgery or accident).Having a family history (parent or sibling) of Type 1 diabetes.Risk factors for Type 1 diabetes include: Who gets diabetes? What are the risk factors?įactors that increase your risk differ depending on the type of diabetes you ultimately develop. More than 26% of adults age 65 and older (about 1 in 4) have diabetes. The number of people who are diagnosed with diabetes increases with age. Some 7.3 million adults aged 18 and older (about 1 in 5) are unaware that they have diabetes (just under 3% of all U.S. Some 34.2 million people of all ages – about 1 in 10 – have diabetes in the U.S. Drug or chemical-induced diabetes: Examples of this type happen after organ transplant, following HIV/AIDS treatment or are associated with glucocorticoid steroid use.ĭiabetes insipidus is a distinct rare condition that causes your kidneys to produce a large amount of urine.Cystic fibrosis-related diabetes: This is a form of diabetes specific to people with this disease.Examples are neonatal diabetes and maturity-onset diabetes of the young. Monogenic diabetes syndromes: These are rare inherited forms of diabetes accounting for up to 4% of all cases. ![]() However, if you have gestational diabetes you're at higher risk of developing Type 2 diabetes later on in life. Gestational diabetes usually goes away after pregnancy. Gestational diabetes : This type develops in some women during their pregnancy.Your blood glucose levels are higher than normal but not high enough to be officially diagnosed with Type 2 diabetes. Prediabetes: This type is the stage before Type 2 diabetes.Your parents or grandparents may have called it “having a touch of sugar.” Other common names for Type 2 include adult-onset diabetes and insulin-resistant diabetes. It usually occurs in middle-aged and older people. ![]() Up to 95% of people with diabetes have Type 2. This is the most common type of diabetes.
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